Are Covid-19 vaccines safe? Read the answer here

First Published Dec 3, 2020, 12:19 PM IST

Even as Covid-19 vaccine development progresses in leaps and bounds, questions are being raised about the efficacy of these medicines. Dr Sanjay Gupta, CNN's Chief Medical Correspondent and Associate Professor of Neurosurgery at the Emory University Hospital, took to Twitter to clear the air surrounding the vaccines. Read on...

<p><strong>Why is it so tricky to distribute these vaccines?</strong><br />
It is in large part because the two vaccines currently under EUA review have to be stored at super cold temperatures. Pfizer's vaccine needs the coldest storage at -70C; -94F and that is unavailable in most places. Pfizer has even &nbsp;designed special 'thermal shippers' to help transport its vaccine. Moderna's vaccine requires storage at -20C; -4F. Also very cold, but doable in most hospitals. Other vaccines like the one from Astrazeneca/Oxford or Johnson &amp; Johnson can be stored at 2-8C; 36-46F. Much easier because a simple refrigerator will do.</p>

Why is it so tricky to distribute these vaccines?
It is in large part because the two vaccines currently under EUA review have to be stored at super cold temperatures. Pfizer's vaccine needs the coldest storage at -70C; -94F and that is unavailable in most places. Pfizer has even  designed special 'thermal shippers' to help transport its vaccine. Moderna's vaccine requires storage at -20C; -4F. Also very cold, but doable in most hospitals. Other vaccines like the one from Astrazeneca/Oxford or Johnson & Johnson can be stored at 2-8C; 36-46F. Much easier because a simple refrigerator will do.

<p><strong>Who gets the vaccine first?</strong><br />
Vaccine advisers to the US Centers for Disease Control and Prevention voted on Wednesday to recommend that both health care workers (21 million) and residents of long-term care facilities (3 million) be vaccinated first.&nbsp;</p>

Who gets the vaccine first?
Vaccine advisers to the US Centers for Disease Control and Prevention voted on Wednesday to recommend that both health care workers (21 million) and residents of long-term care facilities (3 million) be vaccinated first. 

<p><strong>What about the rest of us?&nbsp;</strong><br />
Access to the vaccine will continue to be rolled out in phases. On Wednesday, Lt Gen Paul Ostrowski of the US government's Operation Warp Speed said by June, 'A hundred percent of Americans who want the vaccine will have had the vaccine by that point in time.'</p>

What about the rest of us? 
Access to the vaccine will continue to be rolled out in phases. On Wednesday, Lt Gen Paul Ostrowski of the US government's Operation Warp Speed said by June, 'A hundred percent of Americans who want the vaccine will have had the vaccine by that point in time.'

<p><strong>Could getting vaccinated result in getting an infection?</strong><br />
The answer is no and that's because there is no actual virus in the vaccine, only the genetic code for a portion of the virus. The reason some people feel crummy after is because the vaccine is revving up the immune response.&nbsp;</p>

Could getting vaccinated result in getting an infection?
The answer is no and that's because there is no actual virus in the vaccine, only the genetic code for a portion of the virus. The reason some people feel crummy after is because the vaccine is revving up the immune response. 

<p><strong>Are the vaccines safe?</strong><br />
Both the Pfizer and Moderna vaccine needed to meet a two-month safety threshold before applying for an EUA, but long-term safety of the vaccines is still unknown. Moncef Slaoui, the science adviser of Operation Warp Speed, told CNN: "I always make sure I say that while we know that the short-term -- and I'm going to call it mid-term -- safety of this vaccine is now well understood, the very long-term safety is not yet well understood by definition."</p>

Are the vaccines safe?
Both the Pfizer and Moderna vaccine needed to meet a two-month safety threshold before applying for an EUA, but long-term safety of the vaccines is still unknown. Moncef Slaoui, the science adviser of Operation Warp Speed, told CNN: "I always make sure I say that while we know that the short-term -- and I'm going to call it mid-term -- safety of this vaccine is now well understood, the very long-term safety is not yet well understood by definition."

<p><strong>Will I need to get the vaccine if I’ve already had Covid-19?</strong><br />
Probably. The idea behind a vaccine is it should stage a stronger (and maybe longer) immune response than your body has after a natural infection. We still don’t know how long “natural immunity” from a Covid-19 infection might last.&nbsp;</p>

Will I need to get the vaccine if I’ve already had Covid-19?
Probably. The idea behind a vaccine is it should stage a stronger (and maybe longer) immune response than your body has after a natural infection. We still don’t know how long “natural immunity” from a Covid-19 infection might last. 

<p><strong>Did Moderna really create a vaccine in just two days?</strong><br />
Yes and no. The mRNA platform Moderna uses for its vaccine was developed over many years. But the design for the Covid-19 vaccine was done just in two days. However, if this platform hadn’t already been developed, that two-day timeline would have been impossible</p>

Did Moderna really create a vaccine in just two days?
Yes and no. The mRNA platform Moderna uses for its vaccine was developed over many years. But the design for the Covid-19 vaccine was done just in two days. However, if this platform hadn’t already been developed, that two-day timeline would have been impossible

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