Stomach Pain Alert: 5 Possible Diseases Behind Frequent Discomfort

Published : Nov 08, 2025, 12:02 PM IST

You shouldn't ignore frequent stomach pain. It might be a symptom of certain underlying diseases.

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Causes of Stomach Ache

Occasional stomach discomfort is usually nothing to worry about, likely just indigestion. But persistent, severe stomach pain is a different story. It might not be indigestion at all, but a sign of another illness.

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Gallstones

Stomach pain could be a sign of gallstones. These hard deposits in the gallbladder block bile flow, leading to severe upper abdominal pain, especially after eating fatty foods.

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Gastritis

Caused by infection, stress, or overusing painkillers, this is an inflammation of the stomach lining. It brings a burning pain, nausea, and bloating, often right after eating.

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Reflux Disease

With gastroesophageal reflux disease (GERD), stomach acid often flows back into the esophagus. This can cause heartburn, stomach discomfort, and a sour taste in your mouth.

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Appendicitis

Appendicitis causes severe pain in your lower right abdomen, often with a fever. If you also feel nauseous, see a doctor right away. Surgery is usually needed immediately.

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Ulcer

Pain can come from sores in your stomach or small intestine, often due to H. pylori infection. This causes a burning pain that's worse on an empty stomach. If you have these symptoms, see a doctor.

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