Childhood Blood Pressure at 7 Predicts Midlife Cardiovascular Risk

A landmark study shows children with elevated blood pressure at age 7 face 40–50% higher risk of heart-related death by midlife. Early screening and heart-healthy habits are critical for lifelong cardiovascular health.

Could a single health measurement in childhood shape your future lifespan? A landmark American Heart Association study reveals that blood pressure at age 7 strongly predicts the risk of dying from cardiovascular disease by the mid-50s.

The Power of a Childhood Reading

In the largest study of its kind, researchers tracked more than 38,000 children from the Collaborative Perinatal Project (CPP). Each child had their blood pressure measured at age 7, and survival outcomes were followed through 2016.

Findings, published in JAMA and presented at the American Heart Association’s Hypertension Scientific Sessions 2025 in Baltimore, show a clear link:

• Children in the top 10% of blood pressure for their age, sex, and height faced the highest risk of premature death.
• Both elevated blood pressure (90–94th percentile) and hypertension (≥95th percentile) were tied to a 40–50% higher risk of dying early from heart disease.
• Even moderately higher readings within the “normal” range carried 13–18% increased risk.

Early Advantage, Lifelong Consequences

Dr. Alexa Freedman of Northwestern University Feinberg School of Medicine, lead author of the study, explains:

> “We were surprised to find that even modestly higher blood pressure in childhood predicted serious health risks decades later. Our results highlight the importance of screening children early and encouraging heart-healthy habits from a young age.”

The study also compared siblings within families and found that the child with higher blood pressure was more likely to die from heart disease later — showing the risk wasn’t only due to shared environment or genetics.

Why Children’s Blood Pressure Matters

Experts say this study strengthens calls for routine blood pressure checks in children. Current guidelines from the American Academy of Pediatrics recommend annual screening starting at age 3.

Dr. Bonita Falkner, an American Heart Association expert, who was not involved in the study, notes:

> “Even in childhood, blood pressure is a vital marker of long-term cardiovascular health. Monitoring it carefully could transform how we define and prevent hypertension in kids.”

Study by the Numbers

• 38,252 children enrolled between 1959–1965.
• Survival tracked until 2016.
• 2,837 participants died, including 504 from cardiovascular disease.
• Risk of death rose 40–50% for children with elevated or high blood pressure.

Limitations and Future Directions

Researchers caution that the study relied on a single blood pressure reading at age 7, which may not reflect long-term patterns. The original participants were also mostly Black and white children from the 1960s–70s, so findings may not fully apply to today’s more diverse populations.

Still, the decades-long dataset offers unprecedented insight into how childhood health metrics shape lifelong heart outcomes.

Why This Matters

This research makes one message clear:

• High blood pressure in childhood is not harmless.
• Moderate elevations can still increase lifetime risk.
• Prevention must start early — long before adulthood.

As Freedman concludes: “One number at age 7 may help determine how long you live.”